PUF60 抗体 (AA 346-533)
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北京 101111
Quick Overview for PUF60 抗体 (AA 346-533) (ABIN1886388)
抗原
See all PUF60 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 346-533
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 533 of Human PUF60
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
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别名
- PUF60
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背景
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The protein encoded by this gene is a Ro RNP-binding protein.It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs.This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein.It can repress a c-myc reporter via the FUSE.It is also known to target transcription factor IIH and inhibit activated transcription.This gene is implicated in the xeroderma pigmentosum disorder.There are two alternatively spliced transcript variants of this gene encoding different isoforms.There seems to be evidence of multiple polyadenylation sites for this gene.[provided by RefSeq]
Synonyms: FIR, PUF60, RoBPI -
分子量
- 58 kDa
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基因ID
- 22827
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NCBI登录号
- NP_055096, NM_014281
抗原
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