CCL17 抗体 (AA 338-558)
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北京 101111
Quick Overview for CCL17 抗体 (AA 338-558) (ABIN1886379)
抗原
See all CCL17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 338-558
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 338 and 558 of Human ABCD2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))
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别名
- ABCD2
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背景
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle.All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter.The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease.This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes.This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.[provided by RefSeq]
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分子量
- 83 kDa
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基因ID
- 225
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NCBI登录号
- NM_005164, NP_005155
抗原
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