Coagulation Factor X 抗体 (AA 33-282)
Quick Overview for Coagulation Factor X 抗体 (AA 33-282) (ABIN1886374)
抗原
See all Coagulation Factor X (F10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-282
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 33 and 282 of Human F10
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Coagulation Factor X (F10)
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别名
- Factor X
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背景
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This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade.This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR.Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases.The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway).The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.[provided by RefSeq]
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分子量
- 55 kDa
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基因ID
- 2159
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NCBI登录号
- NM_000504, NP_000495
抗原
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