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PCBP2 抗体 (AA 299-362)

This anti-PCBP2 antibody is a 兔 多克隆 antibody detecting PCBP2 in WB 和 IF. Suitable for 人.
产品编号 ABIN1886337
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PCBP2 抗体 (AA 299-362) (ABIN1886337)

抗原

See all PCBP2 抗体
PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

适用

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宿主

  • 50
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克隆类型

  • 36
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多克隆

标记

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This PCBP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 299-362

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Synthetic peptide contain a sequence corresponding to a region within amino acids 299 and 362 of PCBP2
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

    别名

    PCBP2

    背景

    The protein encoded by this gene appears to be multifunctional.Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins.The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding.Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure.It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2.This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes.Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2).Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
    Synonyms: HNRPE2, MGC110998, hnRNP-E2

    分子量

    38 kDa

    基因ID

    5094

    NCBI登录号

    NM_031989, NP_114366
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