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LIMK2 抗体 (AA 294-665)

LIMK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886331
发货至: 中国
  • 抗原 See all LIMK2 抗体
    LIMK2 (LIM Domain Kinase 2 (LIMK2))
    抗原表位
    • 9
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 294-665
    适用
    • 55
    • 34
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 3
    • 3
    • 2
    • 1
    克隆类型
    • 54
    • 1
    多克隆
    标记
    • 44
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIMK2 antibody is un-conjugated
    应用范围
    • 46
    • 25
    • 21
    • 13
    • 10
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 294 and 665 of LIM kinase 2
    Top Product
    Discover our top product LIMK2 Primary Antibody
  • 应用备注
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.500
    Immunofluorescence: 1.100-1.200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    Biohazard Informations: This product contains thimerosal which is hazardous.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    LIMK2 (LIM Domain Kinase 2 (LIMK2))
    别名
    LIM kinase 2 (LIMK2 产品)
    别名
    xlimk2 antibody, zgc:91990 antibody, wu:fa97c09 antibody, wu:fk73e11 antibody, LIMK2 antibody, Limk2b antibody, Link2 antibody, LIMK antibody, 9430059K01 antibody, A930024P04Rik antibody, C85310 antibody, Limk2a antibody, LIM domain kinase 2 L homeolog antibody, LIM domain kinase 2 antibody, LIM motif-containing protein kinase 2 antibody, limk2.L antibody, limk2 antibody, LIMK2 antibody, Limk2 antibody
    背景
    There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain.LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers.Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions.LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain.The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton.At least three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
    分子量
    78 kDa
    基因ID
    3985
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