WT1 抗体 (AA 277-495)
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北京 101111
Quick Overview for WT1 抗体 (AA 277-495) (ABIN1886304)
抗原
See all WT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 277-495
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 277 and 495 (P19544) of Wilms Tumor 1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- WT1 (Wilms Tumor 1 (WT1))
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别名
- WT1
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背景
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This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus.It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors.Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized.There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.[provided by RefSeq]
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分子量
- 56 kDa
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基因ID
- 7490
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NCBI登录号
- NM_024426, NP_077744
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途径
- Tube Formation
抗原
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