Complement C2 抗体 (AA 265-612)
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Quick Overview for Complement C2 抗体 (AA 265-612) (ABIN1886288)
抗原
See all Complement C2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 265-612
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 265 and 612 of Human C2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Complement C2
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背景
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Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system.Activated C1 cleaves C2 into C2a and C2b.The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase.Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration.This gene localizes within the class III region of the MHC on the short arm of chromosome 6.Alternative splicing results in multiple transcript variants encoding distinct isoforms.Additional transcript variants have been described in publications but their full-length sequence has not been determined.
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分子量
- 83 kDa
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基因ID
- 717
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NCBI登录号
- NP_000054, NM_000063
抗原
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