GALR2 抗体 (AA 243-306)
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Quick Overview for GALR2 抗体 (AA 243-306) (ABIN1886252)
抗原
See all GALR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 243-306
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 243 and 306 of Human GALR2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- GALR2 (Galanin Receptor 2 (GALR2))
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别名
- galanin receptor 2
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背景
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Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis.It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility.The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors.GALR2 interacts with the N-terminal residues of the galanin peptide.The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi.However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.[provided by RefSeq]
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分子量
- 42 kDa
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基因ID
- 8811
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NCBI登录号
- NM_003857, NP_003848
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途径
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
抗原
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