P4HB 抗体 (AA 23-197)
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北京 101111
Quick Overview for P4HB 抗体 (AA 23-197) (ABIN1886225)
抗原
See all P4HB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-197
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 23 and 197 of Human P4HB
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
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别名
- PDI
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背景
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This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family.When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen.This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds.Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.[provided by RefSeq]
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分子量
- 57 kDa
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基因ID
- 5034
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NCBI登录号
- NP_000909, NM_000918
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途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
抗原
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