TPP1 抗体 (AA 224-562)
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北京 101111
Quick Overview for TPP1 抗体 (AA 224-562) (ABIN1886223)
抗原
See all TPP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 224-562
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 224 and 562 of CLN2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- TPP1 (Tripeptidyl Peptidase I (TPP1))
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别名
- CLN2
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背景
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This gene encodes a member of the sedolisin family of serine proteases.The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity.It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification.Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.[provided by RefSeq]
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分子量
- 61 kDa
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基因ID
- 1200
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NCBI登录号
- NP_000382, NM_000391
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途径
- Cell Division Cycle, ER-Nucleus Signaling
抗原
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