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ATRX 抗体 (AA 2161-2413)

This anti-ATRX antibody is a 兔 多克隆 antibody detecting ATRX in WB, IHC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN1886208
发货至: 中国

Quick Overview for ATRX 抗体 (AA 2161-2413) (ABIN1886208)

抗原

See all ATRX 抗体
ATRX (helicase 2, X-linked (ATRX))

适用

  • 73
  • 16
  • 4
  • 3
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  • 2
人, 小鼠

宿主

  • 43
  • 32
  • 1

克隆类型

  • 46
  • 30
多克隆

标记

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  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATRX antibody is un-conjugated

应用范围

  • 29
  • 27
  • 22
  • 19
  • 12
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  • 8
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 6
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 2161-2413

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 2161 and 2413 of ATRX
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    ATRX (helicase 2, X-linked (ATRX))

    别名

    ATRX

    背景

    The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins.The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome.These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes.This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis.Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.[provided by RefSeq]

    分子量

    283 kDa

    基因ID

    546

    NCBI登录号

    NM_000489, NP_000480
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