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GALR2 抗体 (AA 212-277)

This anti-GALR2 antibody is a 兔 多克隆 antibody detecting GALR2 in WB 和 IHC. Suitable for 人.
产品编号 ABIN1886197
发货至: 中国

Quick Overview for GALR2 抗体 (AA 212-277) (ABIN1886197)

抗原

See all GALR2 抗体
GALR2 (Galanin Receptor 2 (GALR2))

适用

  • 42
  • 32
  • 29
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  • 1

宿主

  • 43
  • 1
  • 1

克隆类型

  • 44
  • 1
多克隆

标记

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  • 1
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This GALR2 antibody is un-conjugated

应用范围

  • 33
  • 17
  • 13
  • 13
  • 9
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 4
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    • 1
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    AA 212-277

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Synthetic peptide contain a sequence corresponding to a region within amino acids 212 and 277 of Human GALR2
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    GALR2 (Galanin Receptor 2 (GALR2))

    别名

    galanin receptor 2

    背景

    Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis.It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility.The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors.GALR2 interacts with the N-terminal residues of the galanin peptide.The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi.However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.[provided by RefSeq]

    分子量

    42 kDa

    基因ID

    8811

    NCBI登录号

    NM_003857, NP_003848

    途径

    cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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