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BCCIP 抗体 (AA 181-233)

This anti-BCCIP antibody is a 兔 多克隆 antibody detecting BCCIP in WB 和 IF. Suitable for 人.
产品编号 ABIN1886127
发货至: 中国

Quick Overview for BCCIP 抗体 (AA 181-233) (ABIN1886127)

抗原

See all BCCIP 抗体
BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

适用

  • 36
  • 4
  • 4

宿主

  • 31
  • 5

克隆类型

  • 35
  • 1
多克隆

标记

  • 21
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCCIP antibody is un-conjugated

应用范围

  • 16
  • 14
  • 13
  • 9
  • 9
  • 8
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 181-233

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Synthetic peptide contain a sequence corresponding to a region within amino acids 181 and 233 (Q9P287) of BCCIP
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

    背景

    This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins.It is an evolutionarily conserved nuclear protein with multiple interacting domains.The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium.Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21.This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression.Multiple transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq]

    分子量

    36 kDa

    基因ID

    56647

    NCBI登录号

    NM_016567, NP_057651
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