BCCIP 抗体 (AA 181-233)
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北京 101111
Quick Overview for BCCIP 抗体 (AA 181-233) (ABIN1886127)
抗原
See all BCCIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-233
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 181 and 233 (Q9P287) of BCCIP
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
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背景
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This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins.It is an evolutionarily conserved nuclear protein with multiple interacting domains.The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium.Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21.This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression.Multiple transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq]
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分子量
- 36 kDa
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基因ID
- 56647
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NCBI登录号
- NM_016567, NP_057651
抗原
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