UNC13D 抗体 (AA 1029-1090)
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北京 101111
Quick Overview for UNC13D 抗体 (AA 1029-1090) (ABIN1885943)
抗原
See all UNC13D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1029-1090
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 1029 and 1090 of Human UNC13D
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- UNC13D (Unc-13 Homolog D (UNC13D))
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别名
- UNC13D
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背景
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This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins.The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion.Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.[provided by RefSeq]
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分子量
- 123 kDa
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基因ID
- 201294
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NCBI登录号
- NP_954712, NM_199242
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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