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ALPL 抗体 (AA 1-369)

This anti-ALPL antibody is a 兔 多克隆 antibody detecting ALPL in WB 和 IHC. Suitable for 人.
产品编号 ABIN1885918
发货至: 中国

Quick Overview for ALPL 抗体 (AA 1-369) (ABIN1885918)

抗原

See all ALPL 抗体
ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

适用

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  • 1
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宿主

  • 92
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  • 1

克隆类型

  • 91
  • 30
多克隆

标记

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This ALPL antibody is un-conjugated

应用范围

  • 87
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  • 16
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 13
    • 10
    • 9
    • 5
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    • 4
    • 3
    • 2
    • 2
    • 2
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    • 2
    • 1
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    • 1
    AA 1-369

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 369 of alkaline phosphatase (liver/bone/kidney)
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.50-1.500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

    别名

    alkaline phosphatase(liver/bone/kidney)

    背景

    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific).The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1.The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme.The exact physiological function of the alkaline phosphatases is not known.A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development.This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects.The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.[provided by RefSeq]

    分子量

    57 kDa

    基因ID

    249

    NCBI登录号

    NM_000478, NP_000469
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