Prosaposin 抗体 (AA 1-220)
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北京 101111
Quick Overview for Prosaposin 抗体 (AA 1-220) (ABIN1885798)
抗原
See all Prosaposin (PSAP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-220
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 220 of PSAP
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Prosaposin (PSAP)
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别名
- PSAP
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背景
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This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D.Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites.Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups.The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq]
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分子量
- 58 kDa
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基因ID
- 5660
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NCBI登录号
- NP_002769, NM_002778
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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