PCBP2 抗体 (AA 1-163)
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北京 101111
Quick Overview for PCBP2 抗体 (AA 1-163) (ABIN1885666)
抗原
See all PCBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-163
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 163 of hnRNP E2
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应用备注
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Suggested dilutions:
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
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别名
- hnRNP E2
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背景
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The protein encoded by this gene appears to be multifunctional.Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins.The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding.Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure.It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2.This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes.Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2).Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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分子量
- 38 kDa
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基因ID
- 5094
抗原
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