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GSTM1 抗体 (AA 1-159)

This anti-GSTM1 antibody is a 兔 多克隆 antibody detecting GSTM1 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN1885655
发货至: 中国

Quick Overview for GSTM1 抗体 (AA 1-159) (ABIN1885655)

抗原

See all GSTM1 抗体
GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This GSTM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 21
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    AA 1-159

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 159 of Human GSTM1
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

    别名

    GSTM1

    背景

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class.The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens.Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq]

    分子量

    21 kDa

    基因ID

    2944

    途径

    Negative Regulation of Transporter Activity
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