LOX 抗体 (AA 234-260)
Quick Overview for LOX 抗体 (AA 234-260) (ABIN1882262)
抗原
See all LOX 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 234-260
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预测反应
- M, Pig, Rat
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
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亚型
- IgG2b
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应用备注
- WB: 1:100~500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
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: "LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).
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- LOX (Lysyl Oxidase (LOX))
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别名
- LOX
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背景
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 46944
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NCBI登录号
- NP_002308
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UniProt
- P28300
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途径
- SARS-CoV-2 Protein Interactome
抗原
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