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LOX 抗体 (AA 234-260)

There are 2+ publications for this product available. The 小鼠 单克隆 anti-LOX antibody is suitable to detect LOX in samples from 人. It has been validated for WB.
产品编号 ABIN1882262
发货至: 中国
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Quick Overview for LOX 抗体 (AA 234-260) (ABIN1882262)

抗原

See all LOX 抗体
LOX (Lysyl Oxidase (LOX))

适用

  • 76
  • 37
  • 31
  • 7
  • 1

宿主

  • 80
  • 10
  • 1
小鼠

克隆类型

  • 60
  • 31
单克隆

标记

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This LOX antibody is un-conjugated

应用范围

  • 62
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Western Blotting (WB)

克隆位点

624CT23-7-3
  • 抗原表位

    • 7
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    AA 234-260

    预测反应

    M, Pig, Rat

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.

    亚型

    IgG2b
  • 应用备注

    WB: 1:100~500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Gao, Xiao, Ma, Li, Liu, Feng, Fang, Wu, Han, Zhang, Sun, Wu, Padera, Chen, Wong, Ge, Ji: "LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 18892-7, (2010) (PubMed).

    Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

  • 抗原

    LOX (Lysyl Oxidase (LOX))

    别名

    LOX

    背景

    The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    46944

    NCBI登录号

    NP_002308

    UniProt

    P28300

    途径

    SARS-CoV-2 Protein Interactome
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