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DRD4 抗体 (AA 365-391)

Cited in 4+ publications. This 小鼠 单克隆 anti-DRD4 antibody (Clone 625CT1-5-4) specifically detects DRD4 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1882235
发货至: 中国
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Quick Overview for DRD4 抗体 (AA 365-391) (ABIN1882235)

抗原

See all DRD4 抗体
DRD4 (Dopamine Receptor D4 (DRD4))

适用

  • 60
  • 44
  • 14
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 57
  • 9
小鼠

克隆类型

  • 56
  • 9
单克隆

标记

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  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This DRD4 antibody is un-conjugated

应用范围

  • 51
  • 28
  • 13
  • 13
  • 9
  • 8
  • 5
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)

克隆位点

625CT1-5-4
  • 抗原表位

    • 15
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 365-391

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This DRD4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.

    亚型

    IgG1
  • 应用备注

    WB: 1:100~250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

    Lai, Zhu, Huo, Sun, Yu, Wang, Chai, Li: "Association study of polymorphisms in the promoter region of DRD4 with schizophrenia, depression, and heroin addiction." in: Brain research, Vol. 1359, pp. 227-32, (2010) (PubMed).

    Gadow, Devincent, Olvet, Pisarevskaya, Hatchwell: "Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder." in: The European journal of neuroscience, Vol. 32, Issue 6, pp. 1058-65, (2010) (PubMed).

    Chio, Drong, Riley, Gill, Slightom, Huff: "D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 11813-9, (1994) (PubMed).

  • 抗原

    DRD4 (Dopamine Receptor D4 (DRD4))

    别名

    DRD4

    背景

    This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats.

    分子量

    43901

    NCBI登录号

    NP_000788

    UniProt

    P21917

    途径

    cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
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