DRD4 抗体 (AA 365-391)
Quick Overview for DRD4 抗体 (AA 365-391) (ABIN1882235)
抗原
See all DRD4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 365-391
-
纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
免疫原
- This DRD4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1:100~250
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).
: "Association study of polymorphisms in the promoter region of DRD4 with schizophrenia, depression, and heroin addiction." in: Brain research, Vol. 1359, pp. 227-32, (2010) (PubMed).
: "Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder." in: The European journal of neuroscience, Vol. 32, Issue 6, pp. 1058-65, (2010) (PubMed).
: "D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 11813-9, (1994) (PubMed).
-
: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).
-
- DRD4 (Dopamine Receptor D4 (DRD4))
-
别名
- DRD4
-
背景
- This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats.
-
分子量
- 43901
-
NCBI登录号
- NP_000788
-
UniProt
- P21917
-
途径
- cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
抗原
-