AIM2 抗体
Quick Overview for AIM2 抗体 (ABIN1882191)
抗原
See all AIM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
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免疫原
- This AIM2 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 10-40 region of human AIM2.
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亚型
- IgM
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model." in: Molecular cancer therapeutics, Vol. 5, Issue 1, pp. 1-7, (2006) (PubMed).
: "Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2." in: Biochemical and biophysical research communications, Vol. 326, Issue 2, pp. 417-24, (2004) (PubMed).
: "Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma." in: Oncogene, Vol. 15, Issue 4, pp. 453-7, (1997) (PubMed).
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AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model." in: Molecular cancer therapeutics, Vol. 5, Issue 1, pp. 1-7, (2006) (PubMed).
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- AIM2 (Absent in Melanoma 2 (AIM2))
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别名
- AIM2
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背景
- Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
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分子量
- 38954
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NCBI登录号
- NP_004824
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UniProt
- O14862
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途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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