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AIM2 抗体

This anti-AIM2 antibody is a 小鼠 单克隆 antibody detecting AIM2 in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1882191
发货至: 中国

Quick Overview for AIM2 抗体 (ABIN1882191)

抗原

See all AIM2 抗体
AIM2 (Absent in Melanoma 2 (AIM2))

适用

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宿主

  • 61
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小鼠

克隆类型

  • 66
  • 9
单克隆

标记

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This AIM2 antibody is un-conjugated

应用范围

  • 63
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Western Blotting (WB)

克隆位点

812CT9-2-2-1
  • 纯化方法

    This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

    免疫原

    This AIM2 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 10-40 region of human AIM2.

    亚型

    IgM
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Chen, Ou-Yang, Hung, Liu, Wang, Wang, Hou, Hortobagyi, Hung: "AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model." in: Molecular cancer therapeutics, Vol. 5, Issue 1, pp. 1-7, (2006) (PubMed).

    Cresswell, Clarke, Jackson, Darcy, Trapani, Johnstone: "Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2." in: Biochemical and biophysical research communications, Vol. 326, Issue 2, pp. 417-24, (2004) (PubMed).

    DeYoung, Ray, Su, Anzick, Johnstone, Trapani, Meltzer, Trent: "Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma." in: Oncogene, Vol. 15, Issue 4, pp. 453-7, (1997) (PubMed).

  • 抗原

    AIM2 (Absent in Melanoma 2 (AIM2))

    别名

    AIM2

    背景

    Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

    分子量

    38954

    NCBI登录号

    NP_004824

    UniProt

    O14862

    途径

    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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