Phospholamban 抗体 (N-Term)
(4 references)Quick Overview for Phospholamban 抗体 (N-Term) (ABIN1882182)
抗原
See all Phospholamban (PLN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-22, N-Term
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预测反应
- B, M, Pig, Rb, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PLN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-22 amino acids from the N-terminal region of human PLN.
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亚型
- Ig Fraction
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anti-Phospholamban (PLN) (AA 1-52) antibody
PLN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN 适用: 人 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (pSer16) antibodyPLN 适用: 人 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (N-Term) antibodyVerified PLN 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Phospholamban (PLN) (Thr17) antibodyPLN 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-35) antibodyPLN 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-52) antibodyPLN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) antibodyPLN 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (pThr17) antibodyPLN 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).
: "Mutation of the phospholamban promoter associated with hypertrophic cardiomyopathy." in: Biochemical and biophysical research communications, Vol. 304, Issue 1, pp. 1-4, (2003) (PubMed).
: "The human phospholamban gene: structure and expression." in: Journal of molecular and cellular cardiology, Vol. 31, Issue 3, pp. 679-92, (1999) (PubMed).
: "Structure of the rabbit phospholamban gene, cloning of the human cDNA, and assignment of the gene to human chromosome 6." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11669-75, (1991) (PubMed).
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: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).
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- Phospholamban (PLN)
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别名
- PLN
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背景
- Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2 Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
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分子量
- 6109
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UniProt
- P26678
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途径
- Negative Regulation of Transporter Activity
抗原
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