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GSG2 抗体 (AA 323-352)

This anti-GSG2 antibody is a 兔 多克隆 antibody detecting GSG2 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1882168
发货至: 中国

Quick Overview for GSG2 抗体 (AA 323-352) (ABIN1882168)

抗原

See all GSG2 抗体
GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

适用

  • 29
  • 4
  • 4
  • 2

宿主

  • 26
  • 7

克隆类型

  • 27
  • 6
多克隆

标记

  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GSG2 antibody is un-conjugated

应用范围

  • 16
  • 9
  • 8
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB3404
  • 抗原表位

    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 323-352

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Haspin GSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323~352 amino acids from the central region of human haspin.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Dai, Sultan, Taylor, Higgins: "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment." in: Genes & development, Vol. 19, Issue 4, pp. 472-88, (2005) (PubMed).

    Higgins: "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells." in: Gene, Vol. 267, Issue 1, pp. 55-69, (2001) (PubMed).

    Tanaka, Iguchi, Nakamura, Kohroki, de Carvalho, Nishimune: "Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase." in: Molecular human reproduction, Vol. 7, Issue 3, pp. 211-8, (2001) (PubMed).

  • 抗原

    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

    别名

    Haspin GSG2

    背景

    Post-translational modifications of conserved N-terminal tail residues in histones regulate many aspects of chromosome activity. Mitotic phosphorylation of H3 Thr 3 occurs in prophase and dephosphorylation during anaphase. Haspin, a dual serine/threonine kinase, plays an important role in regulation of chromosome and spindle function during mitosis and meiosis via its function in phosphorylation of the threonine residue in the third position of histone 3 (Thr3).

    分子量

    88495

    NCBI登录号

    NP_114171

    UniProt

    Q8TF76
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