DAPK2 抗体 (N-Term)
Quick Overview for DAPK2 抗体 (N-Term) (ABIN1882166)
抗原
See all DAPK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This DAPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DAPK2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).
: "Lyn kinase promotes erythroblast expansion and late-stage development." in: Blood, Vol. 108, Issue 5, pp. 1524-32, (2006) (PubMed).
: "DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers." in: British journal of cancer, Vol. 86, Issue 11, pp. 1817-23, (2002) (PubMed).
: "Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 2, pp. 464-70, (2002) (PubMed).
: "High frequency of promoter hypermethylation of the death-associated protein-kinase gene in nasopharyngeal carcinoma and its detection in the peripheral blood of patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 2, pp. 433-7, (2002) (PubMed).
: "Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding." in: The EMBO journal, Vol. 20, Issue 5, pp. 1099-113, (2001) (PubMed).
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Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).
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- DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
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别名
- DAPK2
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背景
- DAPK2 belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
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分子量
- 42898
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NCBI登录号
- NP_055141
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UniProt
- Q9UIK4
抗原
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