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YARS2 抗体 (C-Term)

YARS2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14936 unconjugated
产品编号 ABIN1882153
发货至: 中国
  • 抗原 See all YARS2 抗体
    YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 399-427, C-Term
    适用
    • 22
    • 11
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 21
    • 1
    克隆类型
    • 22
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YARS2 antibody is un-conjugated
    应用范围
    • 14
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This YARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the C-terminal region of human YARS2.
    克隆位点
    RB14936
    亚型
    Ig Fraction
    Top Product
    Discover our top product YARS2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Riley, Menezes, Rudinger-Thirion, Duff, de Lonlay, Rotig, Tchan, Davis, Cooper, Christodoulou: "Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia." in: Orphanet journal of rare diseases, Vol. 8, pp. 193, (2014) (PubMed).

    Riley, Cooper, Hickey, Rudinger-Thirion, McKenzie, Compton, Lim, Thorburn, Ryan, Giegé, Bahlo, Christodoulou: "Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome." in: American journal of human genetics, Vol. 87, Issue 1, pp. 52-9, (2010) (PubMed).

    Bonnefond, Frugier, Touzé, Lorber, Florentz, Giegé, Sauter, Rudinger-Thirion: "Crystal structure of human mitochondrial tyrosyl-tRNA synthetase reveals common and idiosyncratic features." in: Structure (London, England : 1993), Vol. 15, Issue 11, pp. 1505-16, (2007) (PubMed).

  • 抗原
    YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))
    别名
    YARS2 (YARS2 产品)
    别名
    2210023C10Rik antibody, tyrRS antibody, CGI-04 antibody, RGD1311696 antibody, MLASA2 antibody, MT-TYRRS antibody, TYRRS antibody, tyrosyl-tRNA synthetase 2 (mitochondrial) antibody, tyrosyl-tRNA synthetase 2 antibody, Yars2 antibody, YARS2 antibody
    背景
    YARS2 catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
    分子量
    53199
    NCBI登录号
    NP_001035526
    UniProt
    Q9Y2Z4
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