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UBE2L6 抗体 (N-Term)

Cited in 4+ publications. This 兔 多克隆 anti-UBE2L6 antibody (Clone RB4156) specifically detects UBE2L6 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN1882146
发货至: 中国
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Quick Overview for UBE2L6 抗体 (N-Term) (ABIN1882146)

抗原

See all UBE2L6 抗体
UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

适用

  • 30
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宿主

  • 25
  • 6

克隆类型

  • 28
  • 3
多克隆

标记

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This UBE2L6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB4156
  • 抗原表位

    • 8
    • 6
    • 5
    • 5
    • 2
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    • 1
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    AA 1-30, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBE2L6.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Takenokuchi, Miyamoto, Saigo, Taniguchi: "Bortezomib Causes ER Stress-related Death of Acute Promyelocytic Leukemia Cells Through Excessive Accumulation of PML-RARA." in: Anticancer research, Vol. 35, Issue 6, pp. 3307-16, (2015) (PubMed).

    Hsiang, Zhao, Krug: "Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cells." in: Journal of virology, Vol. 83, Issue 12, pp. 5971-7, (2009) (PubMed).

    Makki, Heinzel, Englert: "TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels." in: Nucleic acids research, Vol. 36, Issue 12, pp. 4067-78, (2008) (PubMed).

    Kumar, Kao, Howley: "Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13548-54, (1997) (PubMed).

  • 抗原

    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

    别名

    UBE2L6

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

    分子量

    17769

    NCBI登录号

    NP_004214, NP_937826

    UniProt

    O14933
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