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PAPSS1 抗体 (N-Term)

This anti-PAPSS1 antibody is a 兔 多克隆 antibody detecting PAPSS1 in WB. Suitable for 人. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN1882107
发货至: 中国

Quick Overview for PAPSS1 抗体 (N-Term) (ABIN1882107)

抗原

See all PAPSS1 抗体
PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

适用

  • 25
  • 3
  • 2

宿主

  • 22
  • 3

克隆类型

  • 23
  • 2
多克隆

标记

  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAPSS1 antibody is un-conjugated

应用范围

  • 16
  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB5122
  • 抗原表位

    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-30, N-Term

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PAPSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PAPSS1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Gillies, Lee, Long, Ktistakis, Pyne, Pyne: "The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division." in: Cellular signalling, Vol. 21, Issue 5, pp. 675-84, (2009) (PubMed).

    Venkatachalam: "Human 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase: biochemistry, molecular biology and genetic deficiency." in: IUBMB life, Vol. 55, Issue 1, pp. 1-11, (2003) (PubMed).

    Xu, Otterness, Freimuth, Carlini, Wood, Mitchell, Moon, Kim, Xu, Siciliano, Weinshilboum: "Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 437-44, (2000) (PubMed).

    Venkatachalam, Akita, Strott: "Molecular cloning, expression, and characterization of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase and its functional domains." in: The Journal of biological chemistry, Vol. 273, Issue 30, pp. 19311-20, (1998) (PubMed).

    Faiyaz ul Haque, King, Krakow, Cantor, Rusiniak, Swank, Superti-Furga, Haque, Abbas, Ahmad, Ahmad, Cohn: "Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse." in: Nature genetics, Vol. 20, Issue 2, pp. 157-62, (1998) (PubMed).

    Girard, Baekkevold, Amalric: "Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 12, Issue 7, pp. 603-12, (1998) (PubMed).

  • 抗原

    PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

    别名

    PAPSS1

    背景

    Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.

    分子量

    70833

    NCBI登录号

    NP_005434

    UniProt

    O43252

    途径

    Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process
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