Hexokinase 2 抗体 (AA 453-483)
(5 references)Our Local Distributor
北京 101111
Quick Overview for Hexokinase 2 抗体 (AA 453-483) (ABIN1882090)
抗原
See all Hexokinase 2 (HK2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 453-483
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This HK2 (Hexokinase II) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-483 amino acids from the Central region of human HK2 (Hexokinase II).
-
亚型
- Ig Fraction
-
-
anti-Hexokinase 2 (HK2) (AA 1-120) antibody
HK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Hexokinase 2 (HK2) (AA 818-917) antibodyHK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (C-Term) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Hexokinase 2 (HK2) (AA 469-669) antibodyHK2 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 334-526) antibodyHK2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 1-170) antibodyHK2 适用: 人 WB 宿主: 小鼠 Monoclonal 1798CT748-15-25 unconjugated
-
-
应用备注
- WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
: "Combination of platelet-derived growth factor-BB and insulin-like growth factor-I is more effective than platelet-derived growth factor-BB alone in stimulating complete healing of full-thickness..." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Vol. 3, Issue 3, pp. 340-50, (2006) (PubMed).
: "Renal clearance of a recombinant granulocyte colony-stimulating factor, nartograstim, in rats." in: Pharmaceutical research, Vol. 12, Issue 10, pp. 1466-9, (1996) (PubMed).
: "Amino acid substitutions in hexokinase II among patients with NIDDM." in: Diabetes, Vol. 44, Issue 3, pp. 330-4, (1995) (PubMed).
: "Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity." in: Diabetes, Vol. 44, Issue 3, pp. 347-53, (1995) (PubMed).
: "Steady state transcript levels of the type II hexokinase and type 1 glucose transporter in human tumor cell lines." in: Cancer letters, Vol. 82, Issue 1, pp. 27-32, (1994) (PubMed).
-
: "Combination of platelet-derived growth factor-BB and insulin-like growth factor-I is more effective than platelet-derived growth factor-BB alone in stimulating complete healing of full-thickness..." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, Vol. 3, Issue 3, pp. 340-50, (2006) (PubMed).
-
- Hexokinase 2 (HK2)
-
别名
- HK2 (Hexokinase II)
-
背景
- In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated wiht the N-terminus. Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.
-
分子量
- 102380
-
NCBI登录号
- NP_000180
-
UniProt
- P52789
-
途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
抗原
-
