UBE2K 抗体 (AA 109-139)
Quick Overview for UBE2K 抗体 (AA 109-139) (ABIN1882088)
抗原
See all UBE2K 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 109-139
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预测反应
- B
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This HIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-139 amino acids from the Central region of human HIP2.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).
: "Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 1, pp. 128-34, (2000) (PubMed).
: "Recent advances on the pathogenesis of Huntington's disease." in: Experimental neurology, Vol. 157, Issue 1, pp. 1-18, (1999) (PubMed).
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: "Regulation of macrophage-specific gene expression by degenerated lipoproteins." in: Electrophoresis, Vol. 21, Issue 2, pp. 338-46, (2000) (PubMed).
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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别名
- HIP2
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背景
- HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
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分子量
- 22407
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NCBI登录号
- NP_001104582, NP_001104583, NP_005330
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UniProt
- P61086
抗原
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