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DRAK2 抗体 (C-Term)

This anti-DRAK2 antibody is a 兔 多克隆 antibody detecting DRAK2 in WB, IF 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1882073
发货至: 中国

Quick Overview for DRAK2 抗体 (C-Term) (ABIN1882073)

抗原

See all DRAK2 (STK17B) 抗体
DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

适用

  • 38
  • 15
  • 8
  • 1
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人, 小鼠

宿主

  • 35
  • 2
  • 1

克隆类型

  • 37
  • 1
多克隆

标记

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  • 1
  • 1
  • 1
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This DRAK2 antibody is un-conjugated

应用范围

  • 26
  • 21
  • 9
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB3049
  • 抗原表位

    • 7
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    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 342-371, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This DRAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human DRAK2.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Mao, Luo, Han, Bertrand, Wu: "Drak2 is upstream of p70S6 kinase: its implication in cytokine-induced islet apoptosis, diabetes, and islet transplantation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 8, pp. 4762-70, (2009) (PubMed).

    Mao, Qiao, Luo, Wu: "Transgenic drak2 overexpression in mice leads to increased T cell apoptosis and compromised memory T cell development." in: The Journal of biological chemistry, Vol. 281, Issue 18, pp. 12587-95, (2006) (PubMed).

    Sanjo, Kawai, Akira: "DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 44, pp. 29066-71, (1998) (PubMed).

  • 抗原

    DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

    别名

    DRAK2

    背景

    DRAK2 is a novel serine/threonine kinase that induces apoptosis via catalytic activity. DRAKs present high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases. DRAK2 is located in nucleus, and the messenger RNA is ubiquitously expressed in human tissues.

    分子量

    42344

    NCBI登录号

    NP_004217

    UniProt

    O94768
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