ZHX1 抗体 (C-Term)
Quick Overview for ZHX1 抗体 (C-Term) (ABIN1882010)
抗原
See all ZHX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 771-800, C-Term
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ZHX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 771-800 amino acids from the C-terminal region of human ZHX1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension." in: Biochemistry, Vol. 48, Issue 21, pp. 4431-9, (2009) (PubMed).
: "Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression." in: Biochemical and biophysical research communications, Vol. 355, Issue 2, pp. 318-23, (2007) (PubMed).
: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).
: "ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome." in: The Journal of biological chemistry, Vol. 281, Issue 51, pp. 39681-92, (2006) (PubMed).
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: "The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension." in: Biochemistry, Vol. 48, Issue 21, pp. 4431-9, (2009) (PubMed).
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- ZHX1 (Zinc Fingers and Homeoboxes 1 (ZHX1))
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别名
- ZHX1
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背景
- The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants encoding the same protein.
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分子量
- 98098
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NCBI登录号
- NP_001017926, NP_009153
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UniProt
- Q9UKY1
抗原
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