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ZHX1 抗体 (C-Term)

This anti-ZHX1 antibody is a 兔 多克隆 antibody detecting ZHX1 in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1882010
发货至: 中国

Quick Overview for ZHX1 抗体 (C-Term) (ABIN1882010)

抗原

See all ZHX1 抗体
ZHX1 (Zinc Fingers and Homeoboxes 1 (ZHX1))

适用

  • 25
  • 7
  • 6
  • 4
  • 4
  • 3
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  • 2
  • 1

宿主

  • 20
  • 6

克隆类型

  • 22
  • 4
多克隆

标记

  • 21
  • 1
  • 1
  • 1
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  • 1
This ZHX1 antibody is un-conjugated

应用范围

  • 22
  • 15
  • 5
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Western Blotting (WB)

克隆位点

RB40545
  • 抗原表位

    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 771-800, C-Term

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ZHX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 771-800 amino acids from the C-terminal region of human ZHX1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wienk, Lammers, Hotze, Wu, Wechselberger, Owens, Stammers, Stuart, Kaptein, Folkers: "The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension." in: Biochemistry, Vol. 48, Issue 21, pp. 4431-9, (2009) (PubMed).

    Kim, Park, Choi, Kim, Park, Jung, Lee, Oh, Im, Bang, Kim: "Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression." in: Biochemical and biophysical research communications, Vol. 355, Issue 2, pp. 318-23, (2007) (PubMed).

    Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).

    Liu, Clement, Kanwar, Avila-Casado, Chugh: "ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome." in: The Journal of biological chemistry, Vol. 281, Issue 51, pp. 39681-92, (2006) (PubMed).

  • 抗原

    ZHX1 (Zinc Fingers and Homeoboxes 1 (ZHX1))

    别名

    ZHX1

    背景

    The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants encoding the same protein.

    分子量

    98098

    NCBI登录号

    NP_001017926, NP_009153

    UniProt

    Q9UKY1
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