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WASP 抗体 (AA 205-234)

This anti-WASP antibody is a 兔 多克隆 antibody detecting WASP in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881997
发货至: 中国

Quick Overview for WASP 抗体 (AA 205-234) (ABIN1881997)

抗原

See all WASP (WAS) 抗体
WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

适用

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宿主

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克隆类型

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  • 5
多克隆

标记

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This WASP antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40707
  • 抗原表位

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    AA 205-234

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This WAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human WAS.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Almgren, Garamus, Nordstierna, Luc-Blin, Stébé: "Nonideal mixed micelles of fluorinated and hydrogenous surfactants in aqueous solution. NMR and SANS studies of anionic and nonionic systems." in: Langmuir : the ACS journal of surfaces and colloids, Vol. 26, Issue 8, pp. 5355-63, (2010) (PubMed).

    Dovas, Gevrey, Grossi, Park, Abou-Kheir, Cox: "Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages." in: Journal of cell science, Vol. 122, Issue Pt 21, pp. 3873-82, (2009) (PubMed).

    Ameratunga, Woon: "Customised molecular diagnosis of primary immune deficiency disorders in New Zealand: an efficient strategy for a small developed country." in: The New Zealand medical journal, Vol. 122, Issue 1304, pp. 46-53, (2009) (PubMed).

  • 抗原

    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

    别名

    WAS

    背景

    The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.

    分子量

    52913

    NCBI登录号

    NP_000368

    UniProt

    P42768
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