USP14 抗体 (C-Term)
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北京 101111
Quick Overview for USP14 抗体 (C-Term) (ABIN1881985)
抗原
See all USP14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 355-383, C-Term
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预测反应
- B, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This USP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-383 amino acids from the C-terminal region of human USP14.
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亚型
- Ig Fraction
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anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 395-494) antibody
USP14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6D6 unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 395-494) antibodyUSP14 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494) antibodyUSP14 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 1-30), (N-Term) antibodyUSP14 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4334 unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) antibodyUSP14 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) antibodyKD Validated USP14 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2190 unconjugated Recombinant Antibody
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494) antibodyUSP14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) antibodyUSP14 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 9C1 unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 1-494) antibodyUSP14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 14 (USP14) antibodyUSP14 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?." in: Human molecular genetics, Vol. 23, Issue 22, pp. 5928-39, (2014) (PubMed).
: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
: "The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 35, pp. 10909-19, (2009) (PubMed).
: "USP14 inhibits ER-associated degradation via interaction with IRE1alpha." in: Biochemical and biophysical research communications, Vol. 379, Issue 4, pp. 995-1000, (2009) (PubMed).
: "Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5742-52, (2009) (PubMed).
: "Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome." in: Molecular biology of the cell, Vol. 19, Issue 3, pp. 1072-82, (2008) (PubMed).
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: "Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?." in: Human molecular genetics, Vol. 23, Issue 22, pp. 5928-39, (2014) (PubMed).
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- USP14 (Ubiquitin Specific Peptidase 14 (USP14))
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别名
- USP14
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背景
- This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 56069
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NCBI登录号
- NP_001032411, NP_005142
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UniProt
- P54578
抗原
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