UGT2B28 抗体 (AA 218-246)
Quick Overview for UGT2B28 抗体 (AA 218-246) (ABIN1881976)
抗原
See all UGT2B28 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 218-246
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预测反应
- Pr
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This UGT2B28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human UGT2B28.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 229-39, (2010) (PubMed).
: "Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism." in: Human mutation, Vol. 30, Issue 9, pp. 1310-9, (2009) (PubMed).
: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).
: "Isolation and characterization of the UGT2B28 cDNA encoding a novel human steroid conjugating UDP-glucuronosyltransferase." in: Biochemistry, Vol. 40, Issue 13, pp. 3869-81, (2001) (PubMed).
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: "Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 229-39, (2010) (PubMed).
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- UGT2B28 (UDP Glucuronosyltransferase 2 Family, Polypeptide B28 (UGT2B28))
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别名
- UGT2B28
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背景
- UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta-diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active.
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分子量
- 60906
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NCBI登录号
- NP_001193933, NP_444267
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UniProt
- Q9BY64
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途径
- Steroid Hormone Biosynthesis
抗原
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