UBE3C 抗体 (AA 549-578)
Quick Overview for UBE3C 抗体 (AA 549-578) (ABIN1881969)
抗原
See all UBE3C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 549-578
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This UBE3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human UBE3C.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).
: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).
: "A HECT domain E3 enzyme assembles novel polyubiquitin chains." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 19871-8, (2001) (PubMed).
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: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).
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- UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))
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别名
- UBE3C
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背景
- E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'-or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
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分子量
- 123923
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NCBI登录号
- NP_055486
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UniProt
- Q15386
抗原
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