我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

TXNIP 抗体 (N-Term)

Name: TXNIP 抗体 (N-Term)
SKU: ABIN1881962
Availability: OutOfStock

This anti-TXNIP antibody is a 兔多克隆 antibody detecting TXNIP in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.

All lanes : Anti-TXNIP Antibody (N-term) at 1:1000 dilution Lane 1: LNCaP whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. (TXNIP 抗体 (N-Term))

TXNIP Antibody (N-term) (ABIN1881962 and ABIN2838827) western blot analysis in NCI- cell line lysates (35 μg/lane). (TXNIP 抗体 (N-Term))

2 images

(4 references)

产品编号 ABIN1881962

发货至: 中国

Quick Overview for TXNIP 抗体 (N-Term) (ABIN1881962)

抗原

See all TXNIP 抗体

TXNIP (Thioredoxin Interacting Protein (TXNIP))

适用

人

宿主

兔

克隆类型

多克隆

标记

This TXNIP antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB41554

Discover our top product TXNIP Primary Antibody

抗原表位
16

8

8

6

5

3

3

2

2

1

1

1

1

1

1

1

1

1

1
AA 1-30, N-Term

预测反应

M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This TXNIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TXNIP.

亚型

Ig Fraction
anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibody
TXNIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibody
TXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibody
TXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibody
TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibody
TXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibody
TXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 100-150) antibody
TXNIP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Zhuo, Niu, Chen, Xin, Guo, Mao: "Vitamin D3 up-regulated protein 1(VDUP1) is regulated by FOXO3A and miR-17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31491-501, (2010) (PubMed).

Kwon, Won, Suh, Jeon, Shao, Yoon, Chung, Kim, Kim, Nam, Yoon, Kim, Kim, Kim, Kim, Kim, Choi: "Vitamin D3 upregulated protein 1 suppresses TNF-?-induced NF-?B activation in hepatocarcinogenesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3980-9, (2010) (PubMed).

Yu, Chai, He, Hagen, Luo: "Thioredoxin-interacting protein (Txnip) gene expression: sensing oxidative phosphorylation status and glycolytic rate." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25822-30, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
抗原

TXNIP (Thioredoxin Interacting Protein (TXNIP))

别名

TXNIP

背景

TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

分子量

43661

NCBI登录号

NP_006463

UniProt

Q9H3M7

途径

Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome