TXNIP 抗体 (AA 116-145)
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北京 101111
Quick Overview for TXNIP 抗体 (AA 116-145) (ABIN1881961)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 116-145
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预测反应
- Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
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亚型
- Ig Fraction
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anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibodyTXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibodyTXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibodyTXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 100-150) antibodyTXNIP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 121-170) antibodyTXNIP 适用: 人, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000. IHC-P: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "[Growing old]." in: Revue médicale suisse, Vol. 6, Issue 256, pp. 1424, (2010) (PubMed).
: "The role of vitamin D3 upregulated protein 1 in thioacetamide-induced mouse hepatotoxicity." in: Toxicology and applied pharmacology, Vol. 248, Issue 3, pp. 277-84, (2010) (PubMed).
: "Vitamin D3 upregulated protein 1 suppresses TNF-?-induced NF-?B activation in hepatocarcinogenesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3980-9, (2010) (PubMed).
: "p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells." in: FEBS letters, Vol. 584, Issue 15, pp. 3480-5, (2010) (PubMed).
: "TXNIP regulates germinal center generation by suppressing BCL-6 expression." in: Immunology letters, Vol. 129, Issue 2, pp. 78-84, (2010) (PubMed).
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: "[Growing old]." in: Revue médicale suisse, Vol. 6, Issue 256, pp. 1424, (2010) (PubMed).
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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别名
- Txnip
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背景
- May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
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分子量
- 44363
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NCBI登录号
- NP_001009935, NP_076208
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UniProt
- Q8BG60
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途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
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