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TXN 抗体 (C-Term)

This anti-TXN antibody is a 兔 多克隆 antibody detecting TXN in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1881960
发货至: 中国

Quick Overview for TXN 抗体 (C-Term) (ABIN1881960)

抗原

See all TXN 抗体
TXN (Thioredoxin (TXN))

适用

  • 105
  • 39
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 103
  • 48

克隆类型

  • 84
  • 67
多克隆

标记

  • 90
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  • 5
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  • 3
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  • 1
This TXN antibody is un-conjugated

应用范围

  • 114
  • 78
  • 63
  • 44
  • 36
  • 18
  • 16
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB42816
  • 抗原表位

    • 39
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-94, C-Term

    预测反应

    B, M, Pig, Rb, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Zheng, Ma, Sun, Yin, Lin, Liu, Xu, Zeng: "Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity." in: Redox biology, Vol. 14, pp. 237-249, (2018) (PubMed).

  • 抗原

    TXN (Thioredoxin (TXN))

    别名

    TXN

    背景

    Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

    分子量

    11737

    NCBI登录号

    NP_001231867, NP_003320

    UniProt

    P10599

    途径

    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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