TNNC2 抗体 (C-Term)
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北京 101111
Quick Overview for TNNC2 抗体 (C-Term) (ABIN1881894)
抗原
See all TNNC2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 97-126, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TNNC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the C-terminal region of human TNNC2.
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亚型
- Ig Fraction
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anti-Fast Skeletal Troponin C (TNNC2) (AA 2-160) antibody
TNNC2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin C (TNNC2) (AA 1-160) antibodyTNNC2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin C (TNNC2) antibodyTNNC2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin C (TNNC2) (AA 1-160) antibodyTNNC2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin C (TNNC2) (AA 1-160) antibodyTNNC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
: "Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 3, pp. 896-905, (2007) (PubMed).
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
: "Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 9, pp. 4847-52, (1998) (PubMed).
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: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
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- TNNC2 (Fast Skeletal Troponin C (TNNC2))
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别名
- TNNC2
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背景
- Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
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分子量
- 18122
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NCBI登录号
- NP_003270
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UniProt
- P02585
抗原
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