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TNNC2 抗体 (C-Term)

This anti-TNNC2 antibody is a 兔 多克隆 antibody detecting TNNC2 in WB. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881894
发货至: 中国

Quick Overview for TNNC2 抗体 (C-Term) (ABIN1881894)

抗原

See all TNNC2 抗体
TNNC2 (Fast Skeletal Troponin C (TNNC2))

适用

  • 31
  • 20
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  • 1
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人, 小鼠

宿主

  • 30
  • 1

克隆类型

  • 31
多克隆

标记

  • 15
  • 6
  • 1
  • 1
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This TNNC2 antibody is un-conjugated

应用范围

  • 24
  • 14
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  • 1
Western Blotting (WB)

克隆位点

RB32470
  • 抗原表位

    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    AA 97-126, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TNNC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the C-terminal region of human TNNC2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

    Robinson, Lipscomb, Preston, Altin, Watkins, Ashley, Redwood: "Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 3, pp. 896-905, (2007) (PubMed).

    Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

    Vassylyev, Takeda, Wakatsuki, Maeda, Maéda: "Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 9, pp. 4847-52, (1998) (PubMed).

  • 抗原

    TNNC2 (Fast Skeletal Troponin C (TNNC2))

    别名

    TNNC2

    背景

    Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.

    分子量

    18122

    NCBI登录号

    NP_003270

    UniProt

    P02585
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