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TIPIN 抗体 (N-Term)

TIPIN 适用: 人 WB 宿主: 兔 Polyclonal RB40607 unconjugated
产品编号 ABIN1881887
发货至: 中国
  • 抗原 See all TIPIN 抗体
    TIPIN (TIMELESS Interacting Protein (TIPIN))
    抗原表位
    • 13
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 227-254, N-Term
    适用
    • 39
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 31
    • 8
    克隆类型
    • 33
    • 6
    多克隆
    标记
    • 27
    • 3
    • 3
    • 2
    • 2
    • 2
    This TIPIN antibody is un-conjugated
    应用范围
    • 36
    • 20
    • 7
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.
    克隆位点
    RB40607
    亚型
    Ig Fraction
    Top Product
    Discover our top product TIPIN Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Kemp, Akan, Yilmaz, Grillo, Smith-Roe, Kang, Cordeiro-Stone, Kaufmann, Abraham, Sancar, Unsal-Kaçmaz: "Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).

    Leman, Noguchi, Lee, Noguchi: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).

    Gotter, Suppa, Emanuel: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." in: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).

  • 抗原
    TIPIN (TIMELESS Interacting Protein (TIPIN))
    别名
    TIPIN (TIPIN 产品)
    别名
    1110005A05Rik antibody, 1110018P21Rik antibody, RGD1564084 antibody, MGC82649 antibody, zgc:91928 antibody, tipin antibody, TIMELESS interacting protein antibody, timeless interacting protein antibody, timeless interacting protein S homeolog antibody, timeless interacting protein L homeolog antibody, TIPIN antibody, Tipin antibody, tipin.S antibody, tipin antibody, tipin.L antibody
    背景
    Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
    分子量
    34555
    NCBI登录号
    NP_060328
    UniProt
    Q9BVW5
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