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TIPIN 抗体 (N-Term)

There are 3+ publications for this product available. The 兔 多克隆 anti-TIPIN antibody is suitable to detect TIPIN in samples from 人. It has been validated for WB.
产品编号 ABIN1881887
发货至: 中国
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Quick Overview for TIPIN 抗体 (N-Term) (ABIN1881887)

抗原

See all TIPIN 抗体
TIPIN (TIMELESS Interacting Protein (TIPIN))

适用

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宿主

  • 27
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克隆类型

  • 29
  • 6
多克隆

标记

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This TIPIN antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40607
  • 抗原表位

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    AA 227-254, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Kemp, Akan, Yilmaz, Grillo, Smith-Roe, Kang, Cordeiro-Stone, Kaufmann, Abraham, Sancar, Unsal-Kaçmaz: "Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).

    Leman, Noguchi, Lee, Noguchi: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).

    Gotter, Suppa, Emanuel: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." in: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).

  • 抗原

    TIPIN (TIMELESS Interacting Protein (TIPIN))

    别名

    TIPIN

    背景

    Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.

    分子量

    34555

    NCBI登录号

    NP_060328

    UniProt

    Q9BVW5
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