TIPIN 抗体 (N-Term)
Quick Overview for TIPIN 抗体 (N-Term) (ABIN1881887)
抗原
See all TIPIN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 227-254, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).
: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).
: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." in: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).
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Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).
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- TIPIN (TIMELESS Interacting Protein (TIPIN))
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别名
- TIPIN
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背景
- Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
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分子量
- 34555
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NCBI登录号
- NP_060328
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UniProt
- Q9BVW5
抗原
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