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TIAM1 抗体 (C-Term)

This anti-TIAM1 antibody is a 兔 多克隆 antibody detecting TIAM1 in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881884
发货至: 中国

Quick Overview for TIAM1 抗体 (C-Term) (ABIN1881884)

抗原

See all TIAM1 抗体
TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

适用

  • 28
  • 7

宿主

  • 26
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  • 1
  • 1

克隆类型

  • 28
  • 4
多克隆

标记

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  • 1
  • 1
This TIAM1 antibody is un-conjugated

应用范围

  • 25
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  • 6
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Western Blotting (WB)

克隆位点

RB41848
  • 抗原表位

    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1478-1506, C-Term

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Yang, Lv, Liu, Liu, Yang, Hu: "Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma." in: Japanese journal of clinical oncology, Vol. 40, Issue 11, pp. 1053-9, (2010) (PubMed).

    Moriarty, Pursell, Mercurio: "miR-10b targets Tiam1: implications for Rac activation and carcinoma migration." in: The Journal of biological chemistry, Vol. 285, Issue 27, pp. 20541-6, (2010) (PubMed).

    Shepherd, Klaus, Liu, Ramaswamy, DeMali, Fuentes: "The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion." in: Journal of molecular biology, Vol. 398, Issue 5, pp. 730-46, (2010) (PubMed).

  • 抗原

    TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))

    别名

    TIAM1

    背景

    Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.

    分子量

    177508

    NCBI登录号

    NP_003244

    UniProt

    Q13009
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