TIAM1 抗体 (C-Term)
Quick Overview for TIAM1 抗体 (C-Term) (ABIN1881884)
抗原
See all TIAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1478-1506, C-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma." in: Japanese journal of clinical oncology, Vol. 40, Issue 11, pp. 1053-9, (2010) (PubMed).
: "miR-10b targets Tiam1: implications for Rac activation and carcinoma migration." in: The Journal of biological chemistry, Vol. 285, Issue 27, pp. 20541-6, (2010) (PubMed).
: "The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion." in: Journal of molecular biology, Vol. 398, Issue 5, pp. 730-46, (2010) (PubMed).
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: "Up-regulation of Tiam1 and Rac1 correlates with poor prognosis in hepatocellular carcinoma." in: Japanese journal of clinical oncology, Vol. 40, Issue 11, pp. 1053-9, (2010) (PubMed).
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- TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))
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别名
- TIAM1
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背景
- Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
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分子量
- 177508
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NCBI登录号
- NP_003244
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UniProt
- Q13009
抗原
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