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TFEC 抗体 (AA 179-205)

Cited in 3+ publications. This anti-TFEC antibody is a 兔 多克隆 antibody detecting TFEC in WB. Suitable for 人.
产品编号 ABIN1881878
发货至: 中国
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Quick Overview for TFEC 抗体 (AA 179-205) (ABIN1881878)

抗原

See all TFEC 抗体
TFEC (Transcription Factor EC (TFEC))

适用

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宿主

  • 20
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克隆类型

  • 22
  • 1
多克隆

标记

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This TFEC antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40605
  • 抗原表位

    • 6
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    AA 179-205

    预测反应

    C, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Mansky, Sulzbacher, Purdom, Nelsen, Hume, Rehli, Ostrowski: "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter." in: Journal of leukocyte biology, Vol. 71, Issue 2, pp. 304-10, (2002) (PubMed).

    Chung, Kim, Kawamoto: "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells." in: Biochemistry, Vol. 40, Issue 30, pp. 8887-97, (2001) (PubMed).

    Steingrímsson, Tessarollo, Reid, Jenkins, Copeland: "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization." in: Development (Cambridge, England), Vol. 125, Issue 23, pp. 4607-16, (1999) (PubMed).

  • 抗原

    TFEC (Transcription Factor EC (TFEC))

    别名

    TFEC

    背景

    Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.

    分子量

    38788

    NCBI登录号

    NP_001018068, NP_001231512, NP_036384

    UniProt

    O14948
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