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T Antigen (AA 15-43), (N-Term) 抗体

适用: 人 WB, IF 宿主: 兔 Polyclonal RB41833 unconjugated
产品编号 ABIN1881864
发货至: 中国
  • 抗原
    T Antigen
    抗原表位
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-43, N-Term
    适用
    • 18
    • 2
    宿主
    • 11
    • 8
    克隆类型
    • 12
    • 7
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 17
    • 10
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    预测反应
    Chicken,Mouse (Murine)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
    免疫原
    This T antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human T.
    克隆位点
    RB41833
  • 应用备注
    WB: 1:1000,IF: 1:10-50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.39 mg/mL
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
  • Jambhekar, Rekhi, Thorat, Dikshit, Agrawal, Puri: "Revisiting chordoma with brachyury, a \new age\" marker: analysis of a validation study on 51 cases."" in: Archives of pathology & laboratory medicine, Vol. 134, Issue 8, pp. 1181-7, (2010) (PubMed).

    Yang, Ng, Alcorta, Liebsch, Sheridan, Li, Goldstein, Parry, Kelley: "T (brachyury) gene duplication confers major susceptibility to familial chordoma." in: Nature genetics, Vol. 41, Issue 11, pp. 1176-8, (2009) (PubMed).

    Bondue, Lapouge, Paulissen, Semeraro, Iacovino, Kyba, Blanpain: "Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification." in: Cell stem cell, Vol. 3, Issue 1, pp. 69-84, (2008) (PubMed).

    Oakley, Fuhrer, Seethala: "Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 12, pp. 1461-9, (2008) (PubMed).

  • 抗原
    T Antigen
    背景
    The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.

    Synonyms: T, Brachyury protein, Protein T
    NCBI登录号
    NP_003172, NP_001257413
    UniProt
    O15178
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