T Antigen (AA 15-43), (N-Term) 抗体
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Quick Overview for T Antigen (AA 15-43), (N-Term) 抗体 (ABIN1881864)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 15-43, N-Term
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预测反应
- Chicken,Mouse (Murine)
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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免疫原
- This T antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human T.
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应用备注
- WB: 1:1000,IF: 1:10-50
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.39 mg/mL
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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: "Revisiting chordoma with brachyury, a \new age\" marker: analysis of a validation study on 51 cases."" in: Archives of pathology & laboratory medicine, Vol. 134, Issue 8, pp. 1181-7, (2010) (PubMed).
: "T (brachyury) gene duplication confers major susceptibility to familial chordoma." in: Nature genetics, Vol. 41, Issue 11, pp. 1176-8, (2009) (PubMed).
: "Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification." in: Cell stem cell, Vol. 3, Issue 1, pp. 69-84, (2008) (PubMed).
: "Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 12, pp. 1461-9, (2008) (PubMed).
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: "Revisiting chordoma with brachyury, a \new age\" marker: analysis of a validation study on 51 cases."" in: Archives of pathology & laboratory medicine, Vol. 134, Issue 8, pp. 1181-7, (2010) (PubMed).
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- T Antigen
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背景
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The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
Synonyms: T, Brachyury protein, Protein T -
NCBI登录号
- NP_003172, NP_001257413
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UniProt
- O15178
抗原
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