SUB1 抗体 (AA 18-47)
Quick Overview for SUB1 抗体 (AA 18-47) (ABIN1881856)
抗原
See all SUB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 18-47
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预测反应
- Pr
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human SUB1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Human positive coactivator 4 controls heterochromatinization and silencing of neural gene expression by interacting with REST/NRSF and CoREST." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 1-12, (2010) (PubMed).
: "Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics." in: The Journal of biological chemistry, Vol. 284, Issue 32, pp. 21728-37, (2009) (PubMed).
: "Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites." in: The Journal of cell biology, Vol. 183, Issue 5, pp. 769-76, (2008) (PubMed).
: "Activation of p53 function by human transcriptional coactivator PC4: role of protein-protein interaction, DNA bending, and posttranslational modifications." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7603-14, (2007) (PubMed).
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: "Human positive coactivator 4 controls heterochromatinization and silencing of neural gene expression by interacting with REST/NRSF and CoREST." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 1-12, (2010) (PubMed).
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- SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
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别名
- SUB1
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背景
- General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
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分子量
- 14395
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NCBI登录号
- NP_006704
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UniProt
- P53999
抗原
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