SPTLC2 抗体 (AA 372-401)
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北京 101111
Quick Overview for SPTLC2 抗体 (AA 372-401) (ABIN1881828)
抗原
See all SPTLC2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 372-401
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SPTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the Central region of human SPTLC2.
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亚型
- Ig Fraction
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anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (AA 453-561) antibody
SPTLC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (AA 88-562) antibodySPTLC2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (AA 548-562) antibodySPTLC2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (AA 453-560) antibodySPTLC2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (AA 423-562) antibodySPTLC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (C-Term) antibodySPTLC2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (AA 72-121) antibodySPTLC2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 斑马鱼, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (N-Term) antibodySPTLC2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (C-Term) antibodySPTLC2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (C-Term) antibodySPTLC2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).
: "Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 20, pp. 8186-91, (2009) (PubMed).
: "The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase." in: The Plant cell, Vol. 18, Issue 12, pp. 3576-93, (2007) (PubMed).
: "Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?" in: The Biochemical journal, Vol. 405, Issue 1, pp. 157-64, (2007) (PubMed).
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: "Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).
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- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
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别名
- SPTLC2
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背景
- This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.
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分子量
- 62924
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NCBI登录号
- NP_004854
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UniProt
- O15270
抗原
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