电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SPTLC2 抗体 (AA 372-401)

This anti-SPTLC2 antibody is a 兔 多克隆 antibody detecting SPTLC2 in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1881828
发货至: 中国

Quick Overview for SPTLC2 抗体 (AA 372-401) (ABIN1881828)

抗原

See all SPTLC2 抗体
SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

适用

  • 51
  • 37
  • 25
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 54
  • 1

克隆类型

  • 55
多克隆

标记

  • 23
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPTLC2 antibody is un-conjugated

应用范围

  • 51
  • 23
  • 13
  • 7
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB)

克隆位点

RB42738
  • 抗原表位

    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 372-401

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SPTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the Central region of human SPTLC2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Rotthier, Auer-Grumbach, Janssens, Baets, Penno, Almeida-Souza, Van Hoof, Jacobs, De Vriendt, Schlotter-Weigel, Löscher, Vondráček, Seeman: "Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).

    Han, Gupta, Gable, Niranjanakumari, Moitra, Eichler, Brown, Harmon, Dunn: "Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 20, pp. 8186-91, (2009) (PubMed).

    Chen, Han, Dietrich, Dunn, Cahoon: "The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase." in: The Plant cell, Vol. 18, Issue 12, pp. 3576-93, (2007) (PubMed).

    Hornemann, Wei, von Eckardstein: "Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?" in: The Biochemical journal, Vol. 405, Issue 1, pp. 157-64, (2007) (PubMed).

  • 抗原

    SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

    别名

    SPTLC2

    背景

    This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.

    分子量

    62924

    NCBI登录号

    NP_004854

    UniProt

    O15270
You are here:
Chat with us!