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SPANXB1 抗体 (AA 17-47)

SPANXB1 适用: 人 WB 宿主: 兔 Polyclonal RB42680 unconjugated
产品编号 ABIN1881824
发货至: 中国
  • 抗原 See all SPANXB1 抗体
    SPANXB1 (SPANX Family, Member B1 (SPANXB1))
    抗原表位
    • 15
    • 6
    • 6
    • 6
    • 3
    AA 17-47
    适用
    宿主
    • 22
    • 3
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPANXB1 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SPNXB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the Central region of human SPNXB.
    克隆位点
    RB42680
    亚型
    Ig Fraction
    Top Product
    Discover our top product SPANXB1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Hansen, Eichler, Fullerton, Carrell: "SPANX gene variation in fertile and infertile males." in: Systems biology in reproductive medicine, Vol. 55, pp. 18-26, (2010) (PubMed).

    Hansen, Nielsen, Retelska, Larsen, Leffers: "A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family." in: Molecular reproduction and development, Vol. 75, Issue 2, pp. 219-29, (2007) (PubMed).

    Kouprina, Pavlicek, Noskov, Solomon, Otstot, Isaacs, Carpten, Trent, Schleutker, Barrett, Jurka, Larionov: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." in: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).

    Zendman, Zschocke, van Kraats, de Wit, Kurpisz, Weidle, Ruiter, Weiss, van Muijen: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." in: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).

  • 抗原
    SPANXB1 (SPANX Family, Member B1 (SPANXB1))
    Abstract
    SPANXB1 产品
    别名
    B1 antibody, CT11.2 antibody, SPANX-B antibody, SPANXB antibody, SPANX family member B1 antibody, SPANXB1 antibody
    背景
    Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B1 and appears to be a duplication of that locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis.
    分子量
    11840
    NCBI登录号
    NP_115850, NP_620588, NP_663697
    UniProt
    Q9NS25
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