SIKE1 抗体 (N-Term)
Quick Overview for SIKE1 抗体 (N-Term) (ABIN1881808)
抗原
See all SIKE1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 36-63, N-Term
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预测反应
- Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Antisense transcription in the mammalian transcriptome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1564-6, (2005) (PubMed).
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: "Antisense transcription in the mammalian transcriptome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1564-6, (2005) (PubMed).
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- SIKE1 (Suppressor of IKBKE 1 (SIKE1))
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别名
- Sike1
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背景
- Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
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分子量
- 23522
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NCBI登录号
- NP_079955
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UniProt
- Q9CPR7
抗原
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