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RLIM 抗体 (AA 199-227)

This anti-RLIM antibody is a 兔 多克隆 antibody detecting RLIM in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881751
发货至: 中国

Quick Overview for RLIM 抗体 (AA 199-227) (ABIN1881751)

抗原

See all RLIM 抗体
RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

适用

  • 38
  • 19
  • 19
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 33
  • 5

克隆类型

  • 36
  • 2
多克隆

标记

  • 19
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RLIM antibody is un-conjugated

应用范围

  • 38
  • 14
  • 13
  • 5
  • 4
  • 4
  • 2
  • 1
Western Blotting (WB)

克隆位点

RB42228
  • 抗原表位

    • 15
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 199-227

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RLIM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the Central region of human RLIM.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Jonkers, Barakat, Achame, Monkhorst, Kenter, Rentmeester, Grosveld, Grootegoed, Gribnau: "RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation." in: Cell, Vol. 139, Issue 5, pp. 999-1011, (2009) (PubMed).

    Her, Chung: "Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1." in: The Journal of biological chemistry, Vol. 284, Issue 13, pp. 8557-66, (2009) (PubMed).

    Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, (2007) (PubMed).

    Hiratani, Yamamoto, Mochizuki, Ohmori, Taira: "Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions." in: Development (Cambridge, England), Vol. 130, Issue 17, pp. 4161-75, (2003) (PubMed).

    Ostendorff, Peirano, Peters, Schlüter, Bossenz, Scheffner, Bach: "Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors." in: Nature, Vol. 416, Issue 6876, pp. 99-103, (2002) (PubMed).

  • 抗原

    RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

    别名

    RLIM

    背景

    The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.

    分子量

    68549

    NCBI登录号

    NP_057204, NP_899196

    UniProt

    Q9NVW2
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